The Relationship Between Knowledge and Side Effects on Compliance with Anti-Tuberculosis Drug Use in Tuberculosis Patients at Madiun Hospital

Abstract

Tuberculosis (TB) is a disease caused by infection with the Mycobacterium tuberculosis bacteria in the lungs. TB treatment generally takes months and requires strict adherence to medication regimens to avoid the risk of bacterial resistance. This research aims to understand the correlation between the level of patient knowledge and the side effects of Anti-Tuberculosis Drugs (OAT) on patient compliance in using Anti-Tuberculosis Drugs. This study uses a descriptive correlation method with a cross- sectional approach, and the sample was selected through a purposive sampling method. Data collection was carried out by asking Tuberculosis patients who met the criteria to fill out the questionnaire directly. All data obtained were explained using SPSS statistical software, and data analysis was carried out systematically. The results of the study with 44 samples obtained more dominant results were in female gender as many as 22, age >45 years as many as 26, high education as many as 25, unemployed as many as 29 and duration of suffering >3 months as many as 28 respondents. The results obtained showed that there was a significant relationship between knowledge (p value = 0.000) and side effects (p value = 0.002) on compliance with the use of anti-Tuberculosis drugs at Dungus Hospital due to p value <0.05.