Literature Review Study: The Efficacy of Nanoparticle-Based Extracts of Natural Product for Cancer Treatment

Abstract

The development of cancer therapy is increasingly leaning towards more targeted and effective approaches, one of which is through the use of nanoparticles in anticancer therapy delivery. The research method utilized is a literature review, searching for relevant scientific articles using electronic databases such as Elsevier, Google Scholar, and PubMed. Studies focus on nanoparticles derived from natural extracts such as rubber cassava leaves (Manihot glazovii), soursop leaves (Annona muricata), fig leaves (Ficus carica L.), ginger (Curcuma xanthorrhiza), and Vernonia amygdalina leaves. Moreover, soursop leaf extract encapsulated in alginate nanoparticles has shown significant anticancer activity against HepG2 liver cancer cells. This research demonstrates that nanoparticle technology innovation provides significant opportunities in developing safer  and more effective cancer therapies, with the capability to precisely target cancer cells.