Wound Healing Activity Of Anting-Anting Leaf Extract Gel Preparation (Acalypha Indica L.) On The Back Of Male White Rats (Rattus Norvegicus)

Abstract

The wound is caused by the activity of combined with sharp object. Flavonoids, saponins and tannins Acalypha indica L. help the wound healing process. The purpose this study determine the wound healing activity of earring leaf extract gel preparation (Acalypha indica L.) on the back of male white rats (Rattus novergicus). 25 male rats were divided 5 groups. Group I negative control (gel base without extract), group II positive control (Binasol®), group III (1% carbopol base earring leaf extract gel), group IV (1.5% carbopol base earring leaf extract gel), and group V (2% carbopol base earring leaf extract gel). Wound length, erythema, and scab were measured. Data analyzed with SPSS. The results earrings leaf extract gel with base concentrations 1; 1.5; and 2% good physical quality and stability. The wound healing activity of earring leaf extract gel preparation can heal cut wounds in white rats with effective concentration 1% base.